Treatment guidelines for adults with active non-radiographic axial spondyloarthritis recommend the use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Tumor Necrosis Factor-alpha (TNF-alpha) inhibitors. If these first-line treatments don’t work or aren’t suitable, doctors may consider secukinumab or ixekizumab (IL-17 inhibitors). Clinical trials show that upadacitinib, an oral Janus Kinase (JAK) inhibitor, can reduce symptoms and improve the quality of life in Spondyloarthritis (SpA) patients. This effectiveness rivals that of biologics. Clinicians use the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score and/or Visual Analogue Scale (VAS) score to measure this. A cost comparison shows that upadacitinib costs about the same and provides similar health benefits as secukinumab and ixekizumab.
The update suggests considering upadacitinib as an alternative to the National Institute for Health and Care Excellence (NICE) recommended Interleukin (IL)-17 inhibitors. This is especially important if conventional therapy doesn’t control the condition well enough or if TNF-alpha inhibitors aren’t suitable or effective.
Clinical and patient experts highlighted the convenience of upadacitinib over IL-17 inhibitors owing to its oral administration.
🚀 Discover how the AI-driven LabelComp tool is transforming drug safety surveillance! By automating the identification of adverse events in drug labelling, LabelComp enhances accuracy and efficiency, supporting regulatory decision-making and public health. 🌐💊
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🌟 School-based health centres (SBHCs) are improving healthcare for underserved youth across the US! These centres provide vital services, from preventive care to chronic disease management, right where students need them most – in schools. 📚🏥
SBHCs improve academic performance, reduce absenteeism, and enhance overall student well-being. Let’s support these essential centres and ensure every child has access to quality healthcare. 🌟
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🌟 Exciting developments in Abu Dhabi! The Department of Health has introduced new ABA guidelines for Autism Spectrum Disorder, aiming to improve care for People of Determination. This initiative focuses on standardising care, enhancing accessibility, and fostering collaboration between healthcare and education professionals.
Learn more about how these guidelines can make a difference in the lives of individuals with ASD.
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